Oskar Fehr Lecture – Ophthalmology through the Cornea: Lessons I have learned

For his groundbreaking work, Mark J. Mannis, M.D., F.A.C.S. (Sacramento, CA) will be honored with the Oskar Fehr Lecture. The renowned American ophthalmologist will demonstrate by way of examples how the cornea can serve as an important diagnostic tool for a range of diseases not limited to the field of ophthalmology.

The cornea is the first site of the transmission of visual images to the eye. As such, its various forms of pathology impact the range of subspecialties in ophthalmology. In this lecture, Professor Dr. med. Mannis will demonstrate examples of how the cornea becomes an important “diagnostic tool” in a range of diseases. This includes conditions managed by the pediatric ophthalmologist. In addition, the cornea, as a diagnostic tool, can be of importance to the neuro-ophthalmologist. It is now recognized that corneal anatomy plays a major role in our interpretation of pressure measurement in the eye and as such, it becomes of major importance to the glaucoma specialist. A clear cornea is mandatory for precision vitreoretinal surgery, and as such, the cornea specialist partners with the retina specialist in the management of combined anterior and posterior segment pathology. Maintenance of a healthy ocular surface is crucial for the oculoplastic surgeon. And the health of both the corneal epithelium and the endothelium are key to successful cataract surgery. Finally, the cornea may also be the key to the discovery and elucidation of a select group of systemic diseases. Mark Mannis will demonstrate examples of these crucial interfaces between the cornea specialist and other areas of ophthalmology.

Dr. Mark J. Mannis is Professor and Chair of the Department of Ophthalmology & Vision Science, UC Davis Eye Center at the University of California, Davis. He also serves as Medical Director of Sierra Donor Services in Sacramento, California. Dr. Mannis is renowned worldwide as one of the most influential ophthalmologists of our time.

Dr. Mannis has published more than 200 articles in peer reviewed journals, focusing mainly on diagnostics and therapies for diseases of the external eye. He is the author of editorials and six books, including the two-volume work Cornea, which he co-edited with Edward Holland. Cornea was cited as one of the 100 most important texts in ophthalmology of the 20th century. Dr. Mannis served as President of the Cornea Society (2008-2010), President of the Pan-American Association of Ophthalmology (1990-1992), and as editor-in-chief of the journal Cornea (1996-2002) and Vision Pan-America (2002-2012). He is a member of 21 national and international ophthalmological societies and has received 18 awards and honors, including the Life Achievement Award of the American Academy of Ophthalmology, an honorary doctorate of the Universidad Nacional Mayor de San Marcos in Peru, the Cornea Society’s distinguished Claes Dollman Award, and the Castrovejo Medal, the highest honor awarded by the American Cornea Society.

Dr. Mannis has spent the last ten years of his career in efforts to contribute to vision care in Latin America, for which he awarded the Distinguished Scholarly Public Service Award by the Academic Senate of the University of California, Davis.

Saal Helmholtz 15:00 - 16:15 27.09.2019
Symposien Fr15
Chameleon-like Corneal Disorders – 7th joint symposium of the Cornea Society and the Sektion DOG-Kornea
There are hidden causes of corneal erosion. Forme fruste of keratoconus does not show any pathologic signs at the slit-lamp. We know distinct corneal alterations with regard to the general term of the so-called dry eye. Different forms of corneal dystrophies are striking as inflammatory clinical signs associated with recurrent corneal erosion. Acanthamoeba keratitis is often mistaken for a herpetic disease at the beginning of the disorder. Several infantile corneal signs can be a hint to distinct hereditary systemic diseases. The most important decompensation of the cornea represents the Fuchs endothelial corneal dystrophy. MGUS-induced paraproteinemic keratopathy is not well known and shows similar clinical signs with regard to distinct dystrophic, systemic, and inflammatory/immunologic alterations of the cornea. Mark Mannis (Sacramento, USA) will finally present the 3rd Oskar Fehr lecture.
Anthony J. Aldave (Los Angeles)
Walter Lisch (Mainz)
Berthold Seitz, Direktor (Homburg/Saar)
Thomas Reinhard, Klinikdirektor (Freiburg)
Gerd Geerling, Klinikdirektor (Düsseldorf)

Multiple individual and sometimes combined causes can result in corneal erosions. Trauma, dystrophies and degenerative disease are the most common forms of pathogenesis, which will be reviewed and their management described.

Michael W. Belin (Marana)

Forme fruste keratoconus (FFK) was defined as a cornea with no abnormal findings by slit-lamp examination and Placido-based topography, with a fellow eye of clinical keratoconus. In other words, an eye that appears “normal” with 70-year-old examination techniques.  The term is currently being used to categorize normal eyes with positive angle kappa, thin but normal corneas and bilateral “suspicious” maps.  This talk will review/suggest appropriate testing and terminology to minimize ambiguous terms such as FFK.

Claus Cursiefen, Klinikdirektor (Köln)

The dry eye is the most common complaint in the ophthalmological practice. Behind a "harmless" dry eye there can also be serious illnesses. Differential diagnoses are discussed.

Anthony J. Aldave (Los Angeles)

This case-based lecture will present a number of inherited and acquired corneal disorders that share phenotypic features of one or more of the corneal dystrophies. A framework for determining whether corneal opacification is likely due to a dystrophic or non-dystrophic disorder will be presented, based on history, examination findings and the results of ancillary testing.

Berthold Seitz, Direktor (Homburg/Saar)

Acanthamoeba keratitis is a rare but severe ocular disease that is becoming steadily more common. In the early stages, a diagnosis of acanthamoeba keratitis is a special challenge for ophthalmologists because the disease can present symptoms very similar to herpes keratitis or bacterial or mycotic keratitis. Despite the increased number of cases, the disease is still rarely recognized immediately. Up to 90% of patients with acanthamoeba keratitis are originally misdiagnosed. However, timely diagnosis is crucial for a good visual acuity prognosis. If the disease is identified too late, a penetrating keratoplasty is often necessary, and in severe cases, patients may be in danger of losing the infected eye. 

Wolf Lagrèze (Freiburg)

Corneal alterations in childhood may not only lead to amblyopia, photophobia or glare, but can be a hallmark of potentially serious systemic diseases. Hence, their knowledge is essential in pediatric ophthalmology. The talk will give an exemplary overview on the most important congenital and early childhood corneal disorders.

Sophie X. Deng (Los Angeles)

Cornea decompensation is a result of endothelial dysfunction. Common causes and management of corneal decompensation will be discussed.

Walter Lisch (Mainz)

Monoclonal gammopathies are much more common than previously known in Ophthalmology. In the benign form or MGUS, different corneal opacities can be observed, in which the patients having no subjective symptoms or conscious systemic findings other than the corneal opacities. It is therefore to be demanded that in all elderly patients with bilateral unclear corneal findings, serum protein electrophoresis should be performed to include or exclude monoclonal gammopathy.

Mark Mannis (Sacramento)

The corneal specialist interacts with many of the other subspecialty areas in ophthalmology, primarily due to the importance of the cornea in diagnosis and treatment. This lecture will review the critical  tangents of the cornea to pediatric ophthalmology, glaucoma, neuro-ophthalmology, retina, oculoplastic surgery, cataract surgery, and general medicine. The purpose of this lecture is to clarify for both the corneal specialist and other subspecialists in ophthalmology the critical role of the cornea in diagnosis and management.

The Oskar Fehr lecture is given in honour of renowned ophthalmologist Professor Fehr, who was head physician of the Department of Eye Diseases at Rudolf Virchow Hospital in Berlin from 1906. Prof. Fehr practiced there until 1934, when the Nazi authorities banned him from setting foot in the clinic because he was Jewish. In 1939, Prof. Fehr fled with his family to Great Britain, where he practiced ophthalmology into his eighties. He was the first physician to distinguish between granular corneal dystrophy, lattice corneal dystrophy and macular corneal dystrophy.