Highlights in Translational Science

Research provides the basis for the future of ophthalmology. The four sessions of this new format present clinical problems like age-related macular or dry eye syndrome are discussed under clinical and research perspectives, allowing for a more complete view. After each session, the best abstract of the session will be chosen.

Saal 2 15:00 - 16:15 26.09.2019
Symposien Do17
Diagnostics and therapy of dry AMD: Where are we now, where are we going?
Despite intense and ground-breaking work on the genetic factors associated with AMD, no efficacious treatment has been found for dry AMD and its late-stage form geographic atrophy. There has been a focus on targeting the alternative complement pathway but clinical trials have failed so far. Extensive genetic as well as epidemiological studies have not revealed promising new targets or treatment strategies. Moreover, the late onset of the disease and the variability in the natural history of patients make disease prediction as well as clinical trial design challenging. This symposium will present a critical discourse on our current understanding of AMD with an emphasis on pathobiology, computational approaches and systems biology. Concepts, ideas and limitations that likely determine future directions for new treatments will be discussed.
Marius Ueffing, Direktor (Tübingen)
Sascha Fauser (Köln)
Caroline Claver (Rotterdam)
Monika Fleckenstein (Bonn)
Sascha Fauser (Köln)
Anthony P. Adamis, M.D., Global Head of Ophthalmology, Immunology and Infectious Diseases (San Francisco)